Prof. Dr. Valdemar Antônio Paffaro Júnior

 

Linha de Pesquisa

Biologia da interação materno-fetal: estudo dos fenômenos biológicos do ambiente uterino durante a gestação com enfoque na imunologia da reprodução envolvendo as células Natural Killer (NK)

 

 

 

Discentes

Aline Mara Gonçalves (Doutorado)

Mirela Oliveira Barboza e Souza (Mestrado)

 

Colaboradores Externos

 

Artigos Publicados

1. Salles, E. S. L. ; KHODADADI, H. ; JARRAHI, A. ; AHLUWALIA, M. ; Paffaro Jr, V. A. ; COSTIGLIOLA, V. ; YU, J. C. ; HESS, D. C. ; DHANDAPANI, K. M. ; BABAN, B. . Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, v. ., p. 1-4, 2020.
2. DIAS, MAYCON DANIEL ; GOULART, MELISSA ; DALÉCIO, CECILIA ; ENES-MARQUES, SILVIA ; SALLES, ÉVILA DA SILVA LOPES ; VENÂNCIO, MARINA ; PEREIRA, ELISÂNGELA MONTEIRO ; Paffaro, Valdemar Antonio ; INCERPI, ERIKA KRISTINA ; Soncini, Roseli . Metformin influences on respiratory system in obese mice induced by postnatal overnutrition. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, v. 247, p. 96-102, 2018.
3. ZAVAN, B. ; Almeida, E. M. ; Salles, E. S. L. ; Amarante-Paffaro A. M. ; PAffaro Jr, VA . COX-2 plays a role in angiogenic DBA+ uNK cell subsets activation and pregnancy protection in LPS-exposed mice. Placenta (Eastbourne), v. 44, p. 34-45, 2016.
4. ZAVAN, B. ; Amarante-Paffaro, A. ; Paffaro Jr, V. A. . α-ACTIN DOWN REGULATION AND PERFORIN LOSS IN UTERINE NATURAL KILLER CELLS FROM LPS-TREATED PREGNANT MICE. Physiological Research (Print), v. 64, p. 427-432, 2015.
5. ORLANDI, L. ; Enes-Marques, S ; FONSECA, W. F. ; Paffaro Jr, V. A. ; VILELA, F. C. ; Giusti-Paiva, Alexandre . Sickness behavior is accentuated in rats with metabolic disorders induced by a fructose diet. Journal of Neuroimmunology (Print), v. 289, p. 75-83, 2015.
6. BARBOSA, A. F. ; HENRIQUE, R. S. ; LUCHO, A. S. ; PAFFARO, V. ; SCHNEEDORF, J. M. . Action of Chicory Fructooligosaccharides on Biomimetic Membranes. International Journal of Electrochemistry (Print), v. 2014, p. 1-8, 2014.
7. GUERRA, F. R. ; ROSSI JUNIOR, Wagner Costa ; Esteves, A ; Paffaro Jr, V. A. . Morphological study of rats and mice pubic symphysis during pregnancy. Brazilian Journal of Veterinary Research and Animal Science (Impresso), v. 48, p. 361-369, 2012.
8. ZAVAN, Bruno ; CARVALHO, Celiane Cardoso ; Rossi, Wagner Costa ; Paffaro, Andréa Mollica Amarante ; Paffaro, Valdemar Antonio . Splenectomy Delays Uterine Natural Killer Cell Recruitment to Implantation Sites and Prolongs Pregnancy in Mice. The Anatomical Record (Hoboken, N.J. : 2007), v. 17, p. n/a-n/a, 2012.
9. ZAVAN, B. ; Giusti-Paiva, Alexandre ; Soncini, R. ; AMARANTE, A. M. ; Paffaro Jr, V. A. . Immunohistochemical demonstration of blood vessels alpha-actin down regulation in LPS-treated pregnant mice. Physiological Research (Print), v. 1, p. 1-4, 2012.
10. Soncini, Roseli ; Santiago, Michael B. ; Orlandi, Lidiane ; Moraes, Gabriel O.I. ; Peloso, André Luiz M. ; dos Santos, Marcelo H. ; Alves-da-Silva, Geraldo ; Paffaro Jr, Valdemar A. ; Bento, Antonio C. ; Giusti-Paiva, Alexandre . Hypotensive effect of aqueous extract of Averrhoa carambola L. (Oxalidaceae) in rats: An in vivo and in vitro approach. Journal of Ethnopharmacology, v. 133, p. 353-357, 2011.
11. ZAVAN, Bruno ; Paffaro, Andréa Mollica Amarante ; JOAZEIRO, Paulo Pinto ; YAMADA, Áureo Tatsumi ; Paffaro VA Jr . Immunocytochemical Studies of Adhesion Molecules on Mouse UNK Cells and Their Extracellular Matrix Ligands During Mouse Pregnancy. The Anatomical Record (Hoboken, N.J. : 2007), p. NA-NA, 2010.
12. TARSITANO, Christiane Aparecida Badin ; Paffaro V A ; PAULI, José Rodrigo ; SILVA, Gustavo Henrique da ; SAAD, Mario J. ; SALGADO, Ione ; CRUZ-HÖFLING, Maria Alice da ; HYSLOP, And Stephen . Hepatic morphological alterations, glycogen content and cytochrome P450 activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME).. Cell and Tissue Research, v. 329, p. 45-58, 2007.
13. A.K. Sheikhi ; ., C. Tayade ; ., V.A. Paffaro ; ., B.A. Croy ; PAffaro Jr, VA . Are Natural Killer Cells Distributed in Relationship to Nerve Fibers in the Pregnant Mouse Uterus?. Pakistan Journal of Biological Sciences, v. 10, p. 2885-2889, 2007.
14. RANDAZZO-MOURA, Priscila ; LEITE, Gildo Bernardo ; SILVA, Gustavo Henrique ; Paffaro V A ; CINTRA, Adélia Cristina Oliveira ; CRUZ-HÖFLING, Maria Alice da ; RODRIGUES-SIMIONI, Léa ; OSHIMA-FRANCO, Yoko . Study of the myotoxicity of bothropstoxin-i using manganese in mouse phrenic nerve-diaphragm and extensor digitorum longus preparations. Journal of Morphological Sciences, Campinas. São Paulo. BR., v. 23, n.2, p. 237-246, 2006.
15. Arrais-Silva, W. W. ; Paffaro V A ; YAMADA, A. T. ; GIORGIO, S. . Expresson of hipoxia-inducible factor-1a in the cutaneous lesions of BALB/c mice infected with Leishmania amazonensis. Experimental and Molecular Pathology (Print), Estados Unidos, v. 78, n.1, p. 49-54, 2005.
16. TAYADE, Chandra ; FANG, Yuan ; BLACK, G. P. ; V A P Jr ; ERLEBACHER, A ; CROY, B. A. . Differential transcription of Eomes and T-bet during maturation of mouse uterine. Journal of Leukocyte Biology, Estados Unidos, v. 78, n.6, p. 1347-1355, 2005.
17. HEUVEL, MARIANNE J. ; XIE, XUEMEI ; TAYADE, CHANDRAKANT ; PERALTA, CRYSTAL ; FANG, Yuan ; LEONARD, SEAN ; Paffaro, Valdemar A. ; SHEIKHI, ABDOL K. ; MURRANT, CORAL ; ANNE CROY, BARBARA . A Review of Trafficking and Activation of Uterine Natural Killer Cells. American Journal of Reproductive Immunology and Microbiology (Cessou em 1988. Cont. 1046-7408 American Journal of Reproductive Immunology), v. 54, p. 322-331, 2005.
18. Paffaro V A; Bizinotto, M.C. ; JOAZEIRO, Paulo Pinto ; YAMADA, A. T. . Subset Classification Of Mouse Uterine Natural Killer Cells By DBA Lectin Reactivity. Placenta (Eastbourne), EUA, v. 24, n.5, p. 479-488, 2003.
19. Borzychowski, A. M. ; Chantakru, S. ; Minhas, K. ; Paffaro V A ; YAMADA, A. T. ; HONG, H. ; Korach, K. S. ; CROY, B. A. . Functional Analysis of Murine Uterine Natural Killer Cells Genetically Devoid of Estrogen Receptors. Placenta. Placenta (Eastbourne), EUA, v. 24, n.4, p. 403-411, 2003.
20. CROY, B. A. ; ESADEG, S. ; Chantakru, S. ; HEUVEL, Ma Rianne Van Den ; Paffaro V A ; HONG, H. ; BLACK, G. P. ; ASHKAR, A. A. ; KISO, Y. ; ZHANG, J. . Update On Pathways Regulating The Activation Of Uterine Natural Killer Cells, Their Interactions With Decidual Spiral Arteries And Homing Of Their Precursors To The Uterus.. Journal of Reproductive Immunology, EUA, v. 59, n.2, p. 175-91, 2003.
21. CROY, B. A. ; He, H. ; WEI, Q ; MCCARTNEY, D ; ZHANG, J. ; Borzychowski, A. M. ; ASHKAR, A. A. ; BLACK, G. P. ; Paffaro V A ; YAMADA, A. T. . Uterine Natural Killer Cells: Insights To Their Cellular And Molecular Biology From Mouse Models. Reproduction (Cambridge), EUA, v. 126, n.2, p. 149-160, 2003.

 

Capítulos de livros publicados
1. ZAVAN, Bruno ; Salles, E. S. L. ; HORVAT, R. O. ; Amarante-Paffaro, A. ; PAFFARO, V. . Physiological Role of Metalloproteinases During Pregnancy. Physiological Role of Metalloproteinases During Pregnancy. 1ed.Hauppauge: Nova Science Publishers, Inc, 2019, v. 1, p. 131-151.
2. Zavan, Bruno ; Amarante-Paffaro, A. ; Paffaro Jr, V. A. . Uterine Vascular Remodeling and its Clinical Relevance During Pregnancy. In: Dominique Degtyaryov. (Org.). Arterioles: Dynamic Structure, Function and Clinical Analysis. 1ed.Hauppauge: Nova Science Publishers, 2017, v. 1, p. 1-21.
3. Yamada, Aureo T. ; Bianco, Juares R. ; Lippe, Eliana M.O. ; Degaki, Karina Y. ; Dalmorin, A.F. ; Edwards, Andrew K. ; Lima, Patricia D.A. ; Paffaro, Valdemar A. . Unique Features of Endometrial Dynamics During Pregnancy. In: Croy, B. Anne ; YAMADA, A. T.; DEMAYO, F. J. ; ADAMSON, S. L.. (Org.). The Guide to Investigation of Mouse Pregnancy. 1ed.: Elsevier, 2014, v. , p. 163-173.
4. Yamada, Aureo T. ; Lima, Patricia D.A. ; Rätsep, Matthew T. ; Paffaro, Valdemar A. ; Nagata, Tetsuji ; Zorn, M. Telma ; Abrahamsohn, P.A. . Electron Microscopy and Immunoelectromicroscopy Protocols. In: Croy, B. Anne ; YAMADA, A. T.; DEMAYO, F. J. ; ADAMSON, S. L.. (Org.). The Guide to Investigation of Mouse Pregnancy. 1ed.: Elsevier, 2014, v. , p. 557-565.
5. ZAVAN, B. ; Amarante-Paffaro A. M. ; Paffaro Jr, V. A. . Role of Laminin on Uterine Remodeling and Embryo Development during Pregnancy. In: Demetrius C. Adams; Emil O. Garcia. (Org.). Laminins: Structure, Biological Activity and Role in Disease. 1ed.: Nova Publishers, 2013, v. , p. 117-124.
6. D. A. Lima, Patricia ; A. Paffaro, Valdemar ; T. Yamada, Aureo . Part F: Functional Duality of Mouse Uterine Natural Killer Cell in Pregnancy. In: Gérard Chaouat; Olivier Sandra; Nathalie Lédée. (Org.). Immunology of Pregnancy 2013. 1ed.Bentham Science Publishers: BENTHAM SCIENCE PUBLISHERS, 2013, v. , p. 335-359.
7. ZAVAN, B. ; AMARANTE, A. M. ; JOAZEIRO, Paulo Pinto ; YAMADA, A. T. ; Paffaro Jr, V. A. . Evidence for fibronectin role on uterine Natural Killer cells migration, proliferation, differentiation and survival during pregnancy. Current Concepts in Structure, Function and Pathology. 1ed.: , 2012, v. , p. 1-.
8. Amarante-Paffaro, A. ; Paffaro Jr, V. A. ; Hoshida M. S ; FARIA, M. ; BEVILACQUA, E. . Identificação de Proteínas por Imunoistoquímica. Análises de RNA, Proteínas e Metabólitos – Metodologia e Procedimentos Técnicos. 1ed.São Paulo: Santos editora, 2012, v. 1, p. 293-308.